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Xeris Biopharma Holdings stock

XERSNASDAQ

Xeris Biopharma Holdings, Inc., HealthcareISIN US98422E1038

$16.65▲ $0.13 (+0.8%)Closing price of 12 Nov 2026

55Score 55 out of 100, Neutral

Turn on early warning

Price and trend

77 / 100

Price history

+119% in one year

The chart shows daily closes over 8 years, adjusted for stock splits and without dividends. Click into the chart to set a price alert at that price.

Long-term trend

Above the 200-day line: the price is 114% above it.

Trend change

Since July 2026 the 50-day line has been above the 200-day line; the trend has turned up.

Momentum

Overheated: the price has risen very quickly lately (RSI 92).

Distance to the high

The price is at its 52-week high. Largest decline in 8 years: 96% (September 2018 to January 2023).

Chart figures for advanced users
SMA 50$10.24
Average price of the last 50 trading days, shows the short-term trend.
SMA 200$7.78
Average price of the last 200 trading days, shows the long-term trend.
RSI (14)92
Relative strength over the last 14 days on a scale from 0 to 100. Above 70 the price counts as overheated, below 30 as sharply fallen.
MACDabove the signal line
Compares a fast and a slow price average. Above its signal line momentum is rising, below it momentum is fading.
Support$5.29
The lowest closing price of the last twelve months.
Resistance$16.65
The highest closing price of the last twelve months.
Market cap
$3.04B
Div. yield
no dividend
Loss
55.7
on earnings for the next twelve months ($0.30 per share)
Fair value
$23.04

Snapshot

Computed from the data by fixed rules, no AI

  • Xeris Biopharma Holdings, Inc. belongs to the Biotechnology industry (United States) and, with a market value of $3.04B, is number 101 of 289 companies in its industry on MEQIRI.
  • For fiscal 2026, analysts expect on average revenue of $387.9M (up 32.9%) and adjusted earnings per share of $0.01.
  • MEQIRI Score 55 out of 100 (Neutral): rank 337 of 702 in Healthcare, median 53.
Show more
  • Our model puts fair value at $23.04, with the price 28% below it.

In plain words

The numbers on this page in plain words, written by an AI

Strengths

  • Growing faster than its industryRevenue up 70.2% a year since 2020, Biotechnology median 19.4%.Growth 70
  • High return on capitalReturn on invested capital 15% in fiscal 2025, Biotechnology median −24.3%.

Weaknesses

  • DilutionShare count up 276% since 2020.Capital allocation 41
  • High debtDebt 4.63 times equity (latest quarter), Biotechnology median 0.09.Stability 28
  • Interest barely coveredOperating profit covers interest only 1 times.Stability 28
55/ 100
MEQIRI Score
Neutral

Its standout strengths are momentum and technical analysis, while fundamentals and stability hold the score back.

Daily figure as of 13 Nov 2026

How the score is calculated

Score overview

Score since yesterday from 56 to 55.

Fundamental quality fluctuates.

Profit consistency10% of years
Cash conversion (free cash flow to earnings, 12 months)not measured
ROIC (12 months)13.2%
Positive free cash flow10% of years
How this category is measured

Score history

The full history of up to 20 years comes with MEQIRI Pro.

See plans

Crash risk high

How well MEQIRI warns

One of the 30% with the highest crash risk among smaller stocks.

From 2016 to 2025, 36 in 100 such stocks fell 30% or more within a year, against a group average of 23 in 100.

What drives the risk

  • price up very strongly over the past year
  • weak fundamentals
  • high price swings

What lowers it

  • price near its 52-week high
  • stable momentum

Valuation

Valuation signal

Modestly undervalued
Price
$16.65
Fair value
$23.04
Gap to fair value
−28%

In our model the price counts as cheap below $16.46 and expensive above $38.40 (uncertainty high, based on the price swings of the past year).

Calculated with a cost of equity of 9.5%. At 10.5% the fair value would be $19.04, at 8.5% it would be $28.79.

Valuation metrics

no data
123.9
Fair value (model)
$23.04

From the cash-flow model alone; without earnings there is no industry value.

Calculate with your own assumptions

Company performance

This shows several years of history with an automatic assessment.

Revenue

10 years

In the twelve months to 30 Sep 2026, revenue rose 38.4% on the twelve months before. Revenue has grown strongly since 2016, at around 86% per year.

Margins

10 years
  • Gross margin
  • Operating margin
  • Net margin

In fiscal 2025: gross 82%, operating 9%, net 0%.

Debt & balance sheet

latest quarter
4.63
1x
2.15
Cash & equivalents
$131.08M

Debt is elevated. Keep an eye on the interest burden and refinancing.

Earnings

Next earnings
1 Mar 2027in 108 days
Last reported
5 Nov 2026EPS reported $0.06 (expected $0.03)above expectations

Analyst estimates

Earnings estimates have barely changed since 15 Oct 2026.

Fiscal 20265 analysts
Earnings per share
$0.010.0%
Revenue
$387.9M0.0%
Fiscal 20275 analysts
Earnings per share
$0.340.0%
Revenue
$480.03M0.0%

MEQIRI has stored the estimates since 15 Oct 2026. Until 30 days are available, the card shows the change since that day. Mean estimate according to Financial Modeling Prep. No price target and no recommendation.

Company outlook raised

Share price after the results: −2.2%

Low end of the 2026 revenue guidance raised, range now $385 million to $390 million; SG&A to rise about $50 million instead of $45 million.

Supporting passage from the call, verbatim
“Based on our strong first half performance and our conviction in the growth trajectory of this business, we are raising the bottom end of our full year 2026 total revenue guidance to $385 million to $390 million.”

The outlook is not part of the score and not a recommendation to buy or sell.

From the earnings call on 6 Aug 2026 (fiscal Q2 2026), read by AI.

Insiders

Open-market purchases and sales by executives, board members and major holders

All insider purchases

No open-market purchases in the last 6 months. 7 insiders sold, $3.72M in total.

Sales say less than purchases: many insiders sell on a fixed plan, for taxes or to diversify.

  • McCulloch KevinSale

    5 Nov 2026, See Remarks

    Shares
    25,000
    Price
    $12.49
    Value
    $312,215
  • Pieper StevenSale

    2 Nov 2026, See Remarks

    Shares
    5,000
    Price
    $10.23
    Value
    $51,174
  • Hecht BethSale

    2 Nov 2026, See Remarks

    Shares
    25,000
    Price
    $10.23
    Value
    $255,828
Show 20 more
  • McCulloch KevinSale

    2 Nov 2026, See Remarks

    Shares
    15,000
    Price
    $10.23
    Value
    $153,488
  • Pieper StevenSale

    1 Oct 2026, See Remarks

    Shares
    5,000
    Price
    $9.41
    Value
    $47,037
  • McCulloch KevinSale

    1 Oct 2026, See Remarks

    Shares
    15,000
    Price
    $9.41
    Value
    $141,120
  • Hecht BethSale

    1 Oct 2026, See Remarks

    Shares
    16,666
    Price
    $9.41
    Value
    $156,792
  • McCulloch KevinSale

    28 Sept 2026, See Remarks

    Shares
    25,000
    Price
    $10.00
    Value
    $250,000
  • McCulloch KevinSale

    1 Sept 2026, See Remarks

    Shares
    15,000
    Price
    $8.49
    Value
    $127,308
  • Hecht BethSale

    1 Sept 2026, See Remarks

    Shares
    16,666
    Price
    $8.49
    Value
    $141,434
  • Pieper StevenSale

    1 Sept 2026, See Remarks

    Shares
    5,000
    Price
    $8.50
    Value
    $42,500
  • Pieper StevenSale

    12 Aug 2026, See Remarks

    Shares
    5,000
    Price
    $8.50
    Value
    $42,500
  • McCulloch KevinSale

    3 Aug 2026, See Remarks

    Shares
    15,000
    Price
    $8.02
    Value
    $120,240
  • Hecht BethSale

    3 Aug 2026, See Remarks

    Shares
    16,666
    Price
    $8.01
    Value
    $133,553
  • Pieper StevenSale

    7 Jul 2026, See Remarks

    Shares
    27,600
    Price
    $8.52
    Value
    $235,276
  • Pieper StevenSale

    6 Jul 2026, See Remarks

    Shares
    17,400
    Price
    $8.50
    Value
    $147,900
  • McCulloch KevinSale

    1 Jul 2026, See Remarks

    Shares
    90,000
    Price
    $8.03
    Value
    $722,511
  • Hecht BethSale

    1 Jul 2026, See Remarks

    Shares
    16,666
    Price
    $8.03
    Value
    $133,860
  • Halkuff DawnSale

    4 Jun 2026, Board

    Shares
    20,000
    Price
    $6.09
    Value
    $121,886
  • Bormann-Kennedy Barbara-Jean AnneSale

    4 Jun 2026, Board

    Shares
    16,000
    Price
    $6.09
    Value
    $97,507
  • Johnson JohnSale

    4 Jun 2026, Board

    Shares
    15,000
    Price
    $6.09
    Value
    $91,422
  • Persky MarlaSale

    3 Jun 2026, Board

    Shares
    15,500
    Price
    $5.90
    Value
    $91,433
  • Hecht BethSale

    1 Jun 2026, See Remarks

    Shares
    16,667
    Price
    $6.06
    Value
    $100,982

Source: Form 4 filings with the US Securities and Exchange Commission. Grants, option exercises, gifts and tax withholdings are hidden. Not a recommendation to buy.

What happened at Xeris Biopharma Holdings

The key events of the last six months from our own data. A click takes you to the matching card.

Sector comparison

702 rated companies in Healthcare

Rank 337 of 702
337/ 702
This company
55
Sector median
53

Categories against the sector median

ProfitabilityMedian of 702 companies43 (median 38)5 above the median
GrowthMedian of 702 companies70 (median 54)16 above the median
FundamentalsMedian of 702 companies36 (median 46)10 below the median
ValuationMedian of 471 companies with a value62 (median 55)7 above the median
StabilityMedian of 702 companies28 (median 67)39 below the median
Capital allocationMedian of 702 companies41 (median 39)2 above the median
Technical analysisMedian of 702 companies77 (median 69)8 above the median
MomentumMedian of 702 companies96 (median 70)26 above the median

The median is the middle value: half of the companies in the sector lie above it, half below. Categories with too few comparable companies are left out.

Competitors in Biotechnology

The next larger and next smaller companies by market value

All 289 Biotechnology stocks

ETFs that hold Xeris Biopharma Holdings

Held by 11 ETFs on Xetra. Shown per index: the ETF with the largest weight.

Show 5 more

Holdings as reported by the funds via FMP, excluding swap ETFs (their holdings are only collateral).

Data status and sources

Score
Daily value of 13 Nov 2026, recalculated nightly
Price
Closing price of 12 Nov 2026
Latest annual report
Fiscal year 2025, period end 31 Dec 2025
Source
Financial statements, ratios and prices from Financial Modeling Prep (FMP), based on the company's reports. MEQIRI calculates the score and fair value from them.

Mandatory disclosures for this rating

  • ; time horizon around 12 months
  • Rated Neutral, published since 7 Nov 2026 (in the score history since 18 Oct 2026)
  • Valuation signal Fairly valued since 7 Nov 2026
  • End-of-day prices, metrics cached for up to 24 hours
  • Score and fair value are estimates from a disclosed model. They are not facts and not a price target.
  • Produced by SSM Ventures UG (haftungsbeschränkt), responsible person Sven Brostmeyer, Managing Director, automatically according to the disclosed model.
  • Not investment advice. Losses up to and including a total loss are possible. Personal circumstances are not considered.

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