Praxis Precision Medicines stock
PRAXNASDAQPraxis Precision Medicines, Inc., HealthcareISIN US74006W2070
42Score 42 out of 100, Weak
Price and trend
66 / 100
Price history
+89% in one yearThe chart shows daily closes over 6 years, adjusted for stock splits and without dividends. Click into the chart to set a price alert at that price.
Above the 200-day line: the price is 10% above it.
Since October 2026 the 50-day line has been below the 200-day line; the trend has turned down.
Overheated: the price has risen very quickly lately (RSI 75).
The price is 10% below its 52-week high. Largest decline in 6 years: 99% (January 2021 to March 2023).
Chart figures for advanced users
- SMA 50$291.10
- Average price of the last 50 trading days, shows the short-term trend.
- SMA 200$314.43
- Average price of the last 200 trading days, shows the long-term trend.
- RSI (14)75
- Relative strength over the last 14 days on a scale from 0 to 100. Above 70 the price counts as overheated, below 30 as sharply fallen.
- MACDabove the signal line
- Compares a fast and a slow price average. Above its signal line momentum is rising, below it momentum is fading.
- Support$164.09
- The lowest closing price of the last twelve months.
- Resistance$386.33
- The highest closing price of the last twelve months.
Snapshot
Computed from the data by fixed rules, no AI
- Praxis Precision Medicines, Inc. belongs to the Biotechnology industry (United States) and, with a market value of $9.67B, is number 41 of 296 companies in its industry on MEQIRI.
- MEQIRI Score 42 out of 100 (Weak): rank 526 of 714 in Healthcare, median 53.
In plain words
The numbers on this page in plain words, written by an AI
Strengths
- More cash than debtCash $599.33M, financial debt $110K.Stability 69
Weaknesses
- Loss-makingLoss of $303.27M over the last 12 months.Fundamentals 17
- Negative free cash flowFree cash flow −$249.12M over the last 12 months.Fundamentals 17
- Volatile share priceVolatility 75% a year over the last 12 months.Stability 69
Its standout strength is momentum, while fundamentals and profitability hold the score back.
Daily figure as of 12 Nov 2026
How the score is calculatedScore overview
Fundamental quality fluctuates.
Score history
The full history of up to 20 years comes with MEQIRI Pro.
See plansValuation
Valuation signal
not measuredNo fair value can be calculated for this stock, so the signal follows the valuation grade.
Valuation metrics
No fair value can be calculated for this stock from the available figures.
Calculate with your own assumptionsCompany performance
This shows several years of history with an automatic assessment.
Revenue
Margins
- Gross margin
- Operating margin
- Net margin
In fiscal 2025: gross 0%, operating 0%, net 0%.
Debt & balance sheet
latest quarterDebt is low; no interest coverage is reported.
Earnings
- Next earnings
- 18 Feb 2027in 98 days
- Last reported
- 9 Nov 2026EPS reported −$3.23 (expected −$3.54)above expectations
Analyst estimates
Analysts have cut their 2027 earnings estimate by 3.8% since 15 Oct 2026. Falling estimates often precede bad news.
- Earnings per share
- −$13.57+0.2%
- Revenue
- $716.67K−31.9%
- Earnings per share
- −$10.32−3.8%
- Revenue
- $343.2M−1.5%
MEQIRI has stored the estimates since 15 Oct 2026. Until 30 days are available, the card shows the change since that day. Mean estimate according to Financial Modeling Prep. No price target and no recommendation.
Company outlook confirmed
Share price after the results: +13.0%No visible change: approvals for two drugs expected in about six months, with G&A rising in the second half to support planned launches.
“We expect G&A will pick up more in the second half of this year to support our planned upcoming launches.”The outlook is not part of the score and not a recommendation to buy or sell.
From the earnings call on 6 Aug 2026 (fiscal Q2 2026), read by AI.
Insiders
Open-market purchases and sales by executives, board members and major holders
No open-market purchases in the last 6 months. One insider sold, $3.61M in total.
Sales say less than purchases: many insiders sell on a fixed plan, for taxes or to diversify.
- DeSimone JillSale
24 Jun 2026, Board
- Shares
- 11,600
- Price
- $311.32
- Value
- $3.61M
Partial trades from one filing are shown in one row, with the average price.
Source: Form 4 filings with the US Securities and Exchange Commission. Grants, option exercises, gifts and tax withholdings are hidden. Not a recommendation to buy.
What happened at Praxis Precision Medicines
The key events of the last six months from our own data. A click takes you to the matching card.
Sector comparison
714 rated companies in Healthcare
- This company
- 42
- Sector median
- 53
Categories against the sector medianMedian of 714 companies
The median is the middle value: half of the companies in the sector lie above it, half below. Categories with too few comparable companies are left out.
Competitors in Biotechnology
The next larger and next smaller companies by market value
- Spyre TherapeuticsSYRE $10.14B48
- TG TherapeuticsTGTX $10.07B65
- Genscript Biotech1548.HK $9.96B48
- Haisco Pharmaceutical Group002653.SZ $9.92B68
- Alteogen196170.KQ $9.56B57
- Krystal BiotechKRYS $9.15B66
- Protagonist TherapeuticsPTGX $8.73B68
- RemeGen688331.SS $8.33B44
ETFs that hold Praxis Precision Medicines
Held by 15 ETFs on Xetra. Shown per index: the ETF with the largest weight.
| ETF | Weight | Cost | Fund size |
|---|---|---|---|
| Global X Genomics & Biotechnology UCITS ETFGN0M | 2.31% | 0.50% | €127.06M |
| Harbor Health Care UCITS ETF AccW311 | 1.01% | 0.89% | €11.61M |
| iShares Nasdaq US Biotechnology UCITS ETF2B70 | 0.48% | 0.35% | €1.21B |
Show 5 more
| State Street SPDR Russell 2000 U.S. Small Cap UCITS ETF (Acc)ZPRR | 0.28% | 0.30% | €4.22B |
| Xtrackers Russell 2000 UCITS ETF 1CXRS2 | 0.28% | 0.30% | €2.17B |
| L&G Russell 2000 US Small Cap Quality UCITS ETFETLZ | 0.14% | 0.30% | €185.82M |
| iShares MSCI USA Small Cap CTB Enhanced ESG UCITS ETFSXRG | 0.10% | 0.43% | €2.48B |
| iShares MSCI World Small Cap CTB Enhanced ESG UCITS ETFCBUG | 0.08% | 0.35% | €434.1M |
Holdings as reported by the funds via FMP, excluding swap ETFs (their holdings are only collateral).
Data status and sources
- Score
- Daily value of 12 Nov 2026, recalculated nightly
- Price
- Closing price of 11 Nov 2026
- Latest annual report
- Fiscal year 2025, period end 31 Dec 2025
- Source
- Financial statements, ratios and prices from Financial Modeling Prep (FMP), based on the company's reports. MEQIRI calculates the score and fair value from them.
Mandatory disclosures for this rating
- ; time horizon around 12 months
- Rated Weak, published since 7 Nov 2026 (in the score history since 31 Oct 2021)
- End-of-day prices, metrics cached for up to 24 hours
- Score and fair value are estimates from a disclosed model. They are not facts and not a price target.
- Produced by SSM Ventures UG (haftungsbeschränkt), responsible person Sven Brostmeyer, Managing Director, automatically according to the disclosed model.
- Not investment advice. Losses up to and including a total loss are possible. Personal circumstances are not considered.