OPKO Health stock
OPKNASDAQOPKO Health, Inc., HealthcareISIN US68375N1037
37Score 37 out of 100, Weak
Price and trend
83 / 100
Price history
+27% in one yearThe chart shows daily closes over 20 years, adjusted for stock splits and without dividends. Click into the chart to set a price alert at that price.
Above the 200-day line: the price is 23% above it.
Since July 2026 the 50-day line has been above the 200-day line; the trend has turned up.
Normal: the price is neither overheated nor sold off (RSI 57).
The price is 5.6% below its 52-week high. Largest decline in 20 years: 95% (June 2015 to March 2024).
Chart figures for advanced users
- SMA 50$1.60
- Average price of the last 50 trading days, shows the short-term trend.
- SMA 200$1.36
- Average price of the last 200 trading days, shows the long-term trend.
- RSI (14)57
- Relative strength over the last 14 days on a scale from 0 to 100. Above 70 the price counts as overheated, below 30 as sharply fallen.
- MACDbelow the signal line
- Compares a fast and a slow price average. Above its signal line momentum is rising, below it momentum is fading.
- Support$1.10
- The lowest closing price of the last twelve months.
- Resistance$1.77
- The highest closing price of the last twelve months.
Snapshot
Computed from the data by fixed rules, no AI
- OPKO Health, Inc. belongs to the Medical (Diagnostics & Research) industry (United States) and, with a market value of $1.24B, is number 33 of 37 companies in its industry on MEQIRI.
- In fiscal 2025 it reported revenue of $606.88M (down 14.9% year on year) and a loss of $225.68M.
- For fiscal 2026, analysts expect on average revenue of $420.6M (down 30.7%) and adjusted earnings per share of −$0.21.
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- MEQIRI Score 37 out of 100 (Weak): rank 581 of 702 in Healthcare, median 53.
In plain words
The numbers on this page in plain words, written by an AI
Strengths
None of our strength checks applies.
Weaknesses
- Revenue shrinkingRevenue down 15.8% a year since 2020.Growth 5
- Loss-makingLoss of $148.06M over the last 12 months.Fundamentals 17
- Turned to a lossEarnings per share from $0.05 in 2020 to −$0.30.Growth 5
Its standout strengths are momentum and technical analysis, while fundamentals and growth hold the score back.
Daily figure as of 13 Nov 2026
How the score is calculatedScore overview
Fundamental quality fluctuates.
Score history
The full history of up to 20 years comes with MEQIRI Pro.
See plansValuation
Valuation signal
not measuredNo fair value can be calculated for this stock, so the signal follows the valuation grade.
Valuation metrics
No fair value can be calculated for this stock from the available figures.
Calculate with your own assumptionsCompany performance
This shows several years of history with an automatic assessment.
Revenue
In the twelve months to 30 Sep 2026, revenue fell 21.9% on the twelve months before. Revenue turned from negative at the start of the period to positive ($606.88M in the latest year).
Margins
- Gross margin
- Operating margin
- Net margin
In fiscal 2025: gross 21%, operating −36%, net −37%. Last 12 months: net −30%.
Debt & balance sheet
latest quarterDebt is moderate, but interest coverage is weak. Keep an eye on the interest burden and refinancing.
Earnings
- Next earnings
- 25 Feb 2027in 104 days
- Last reported
- 4 Nov 2026EPS reported −$0.05 (expected −$0.07)above expectations
Analyst estimates
Analysts have cut their 2027 earnings estimate by 5.6% since 15 Oct 2026. Falling estimates often precede bad news.
- Earnings per share
- −$0.21+5.3%
- Revenue
- $420.6M−26.2%
- Earnings per share
- −$0.29−5.6%
- Revenue
- $314.25M−46.6%
MEQIRI has stored the estimates since 15 Oct 2026. Until 30 days are available, the card shows the change since that day. Mean estimate according to Financial Modeling Prep. No price target and no recommendation.
Company outlook raised
Share price after the results: +35.2%Guidance raised: 2026 total revenue now $560 million to $585 million.
“For the year, we now expect an increase to our previously issued guidance with total revenue now expected to be between $560 million and $585 million, with revenue from services contributing $296 million to $306 million and pharmaceutical product revenue of $164 million to $174 million, while other revenue from our …”The outlook is not part of the score and not a recommendation to buy or sell.
From the earnings call on 27 Jul 2026 (fiscal Q2 2026), read by AI.
Insiders
Open-market purchases and sales by executives, board members and major holders
No open-market purchases in the last 6 months. One insider sold, $24,577 in total.
Sales say less than purchases: many insiders sell on a fixed plan, for taxes or to diversify.
- Paganelli John ASale
5 Nov 2026, Board
- Shares
- 13,601
- Price
- $1.81
- Value
- $24,577
Partial trades from one filing are shown in one row, with the average price.
Source: Form 4 filings with the US Securities and Exchange Commission. Grants, option exercises, gifts and tax withholdings are hidden. Not a recommendation to buy.
What happened at OPKO Health
The key events of the last six months from our own data. A click takes you to the matching card.
Sector comparison
702 rated companies in Healthcare
- This company
- 37
- Sector median
- 53
Categories against the sector medianMedian of 702 companies
The median is the middle value: half of the companies in the sector lie above it, half below. Categories with too few comparable companies are left out.
Competitors in Medical (Diagnostics & Research)
The next larger and next smaller companies by market value
- NeoGenomicsNEO $2.15B39
- VeracyteVCYT $1.99B53
- PersonalisPSNL $1.72B41
- GeneDx HoldingsWGS $1.55B37
- Castle BiosciencesCSTL $1.06B45
- Fulgent GeneticsFLGT $694.28M36
- Myriad GeneticsMYGN $544.84M40
- VoxelVOX.WA $400.11M82
ETFs that hold OPKO Health
Held by 9 ETFs on Xetra. Shown per index: the ETF with the largest weight.
| ETF | Weight | Cost | Fund size |
|---|---|---|---|
| iShares Ageing Population UCITS ETF2B77 | 0.08% | 0.40% | €807M |
| State Street SPDR Russell 2000 U.S. Small Cap UCITS ETF (Acc)ZPRR | 0.03% | 0.30% | €4.28B |
| Xtrackers Russell 2000 UCITS ETF 1CXRS2 | 0.02% | 0.30% | €2.22B |
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| State Street SPDR MSCI USA Small Cap Value Weighted UCITS ETFZPRV | 0.01% | 0.30% | €944.34M |
| iShares MSCI World Small Cap UCITS ETFIUSN | 0.01% | 0.35% | €8.27B |
| iShares MSCI USA Small Cap CTB Enhanced ESG UCITS ETFSXRG | 0.01% | 0.43% | €2.5B |
| UBS MSCI USA Select Factor Mix UCITS ETF USD accUSUE | 0.00% | 0.25% | €175.89M |
| State Street SPDR MSCI All Country World Investable Market UCITS ETF (Acc)SPYI | 0.00% | 0.17% | €8.84B |
Holdings as reported by the funds via FMP, excluding swap ETFs (their holdings are only collateral).
Data status and sources
- Score
- Daily value of 13 Nov 2026, recalculated nightly
- Price
- Closing price of 12 Nov 2026
- Latest annual report
- Fiscal year 2025, period end 31 Dec 2025
- Source
- Financial statements, ratios and prices from Financial Modeling Prep (FMP), based on the company's reports. MEQIRI calculates the score and fair value from them.
Mandatory disclosures for this rating
- ; time horizon around 12 months
- Rated Weak, published since 7 Nov 2026 (in the score history since 31 Jan 2022)
- End-of-day prices, metrics cached for up to 24 hours
- Score and fair value are estimates from a disclosed model. They are not facts and not a price target.
- Produced by SSM Ventures UG (haftungsbeschränkt), responsible person Sven Brostmeyer, Managing Director, automatically according to the disclosed model.
- Not investment advice. Losses up to and including a total loss are possible. Personal circumstances are not considered.