Maze Therapeutics stock
MAZENASDAQMaze Therapeutics, Inc., HealthcareISIN US5787841007
45Score 45 out of 100, Weak
Price and trend
70 / 100
Price history
+11% in one yearThe chart shows daily closes over 2 years, adjusted for stock splits and without dividends. Click into the chart to set a price alert at that price.
Above the 200-day line: the price is 15% above it.
Since May 2026 the 50-day line has been below the 200-day line; the trend has turned down.
Overheated: the price has risen very quickly lately (RSI 73).
The price is 30% below its 52-week high. Largest decline in 2 years: 57% (March 2026 to September 2026).
Chart figures for advanced users
- SMA 50$28.51
- Average price of the last 50 trading days, shows the short-term trend.
- SMA 200$31.42
- Average price of the last 200 trading days, shows the long-term trend.
- RSI (14)73
- Relative strength over the last 14 days on a scale from 0 to 100. Above 70 the price counts as overheated, below 30 as sharply fallen.
- MACDabove the signal line
- Compares a fast and a slow price average. Above its signal line momentum is rising, below it momentum is fading.
- Support$22.39
- The lowest closing price of the last twelve months.
- Resistance$51.84
- The highest closing price of the last twelve months.
Snapshot
Computed from the data by fixed rules, no AI
- Maze Therapeutics, Inc. belongs to the Biotechnology industry (United States) and, with a market value of $2.2B, is number 120 of 289 companies in its industry on MEQIRI.
- MEQIRI Score 45 out of 100 (Weak): rank 458 of 702 in Healthcare, median 53.
In plain words
The numbers on this page in plain words, written by an AI
Strengths
- More cash than debtCash $341.92M, financial debt $23.31M (fiscal 2025).Stability 69
Weaknesses
- Loss-makingLoss of $151.47M over the last 12 months.Fundamentals 17
- Negative free cash flowFree cash flow −$115.26M over the last 12 months.Fundamentals 17
- Volatile share priceVolatility 67% a year over the last 12 months.Stability 69
Its standout strengths are momentum and technical analysis, while capital allocation and fundamentals hold the score back.
Daily figure as of 13 Nov 2026
How the score is calculatedScore overview
Score since yesterday from 46 to 45.
Fundamental quality fluctuates.
Score history
The full history of up to 20 years comes with MEQIRI Pro.
See plansValuation
Valuation signal
not measuredNo fair value can be calculated for this stock, so the signal follows the valuation grade.
Valuation metrics
No fair value can be calculated for this stock from the available figures.
Calculate with your own assumptionsCompany performance
This shows several years of history with an automatic assessment.
Revenue
Margins
- Gross margin
- Operating margin
- Net margin
In fiscal 2025: gross 0%, operating 0%, net 0%. Last 12 months: net −100%.
Debt & balance sheet
Fiscal 2025Debt is low; no interest coverage is reported.
Earnings
- Next earnings
- 24 Mar 2027in 131 days
- Last reported
- 9 Nov 2026EPS reported −$0.79 (expected −$0.76)below expectations
Analyst estimates
Earnings estimates have barely changed since 15 Oct 2026.
- Earnings per share
- −$2.76+0.5%
- Revenue
- $20M0.0%
- Earnings per share
- −$3.21+0.9%
- Revenue
- $10.81M−11.1%
MEQIRI has stored the estimates since 15 Oct 2026. Until 30 days are available, the card shows the change since that day. Mean estimate according to Financial Modeling Prep. No price target and no recommendation.
Insiders
Open-market purchases and sales by executives, board members and major holders
No open-market purchases in the last 6 months. 4 insiders sold, $11.81M in total.
Sales say less than purchases: many insiders sell on a fixed plan, for taxes or to diversify.
- Coloma Jason VSale
2 Nov 2026, Chief Executive Officer
- Shares
- 34,501
- Price
- $30.25
- Value
- $1.04M
- Dandekar AtulSale
29 Oct 2026, CSBO
- Shares
- 7,500
- Price
- $32.07
- Value
- $240,532
- Coloma Jason VSale
1 Oct 2026, Chief Executive Officer
- Shares
- 34,501
- Price
- $27.02
- Value
- $932,260
Show 29 more
- Bernstein HaroldSale
1 Oct 2026, President, R&D & CMO
- Shares
- 16,141
- Price
- $26.93
- Value
- $434,743
- Dandekar AtulSale
29 Sept 2026, CSBO
- Shares
- 7,500
- Price
- $27.06
- Value
- $202,921
- Bernstein HaroldSale
4 Sept 2026, President, R&D & CMO
- Shares
- 9,705
- Price
- $26.22
- Value
- $254,502
- Courtney PhillipsSale
3 Sept 2026, GC and Corp. Secretary
- Shares
- 2,012
- Price
- $26.01
- Value
- $52,334
- Dandekar AtulSale
3 Sept 2026, CSBO
- Shares
- 3,243
- Price
- $26.01
- Value
- $84,354
- Coloma Jason VSale
3 Sept 2026, Chief Executive Officer
- Shares
- 11,411
- Price
- $26.01
- Value
- $296,807
- Bernstein HaroldSale
3 Sept 2026, President, R&D & CMO
- Shares
- 5,189
- Price
- $26.01
- Value
- $134,969
- Courtney PhillipsSale
2 Sept 2026, GC and Corp. Secretary
- Shares
- 1,981
- Price
- $26.47
- Value
- $52,432
- Dandekar AtulSale
2 Sept 2026, CSBO
- Shares
- 3,191
- Price
- $26.47
- Value
- $84,457
- Coloma Jason VSale
2 Sept 2026, Chief Executive Officer
- Shares
- 11,227
- Price
- $26.47
- Value
- $297,148
- Bernstein HaroldSale
2 Sept 2026, President, R&D & CMO
- Shares
- 5,106
- Price
- $26.47
- Value
- $135,142
- Coloma Jason VSale
1 Sept 2026, Chief Executive Officer
- Shares
- 34,501
- Price
- $26.29
- Value
- $906,999
- Bernstein HaroldSale
1 Sept 2026, President, R&D & CMO
- Shares
- 16,141
- Price
- $26.36
- Value
- $425,512
- Dandekar AtulSale
28 Aug 2026, CSBO
- Shares
- 7,500
- Price
- $27.58
- Value
- $206,824
- Bernstein HaroldSale
13 Aug 2026, President, R&D & CMO
- Shares
- 16,142
- Price
- $27.61
- Value
- $445,621
- Coloma Jason VSale
3 Aug 2026, Chief Executive Officer
- Shares
- 34,501
- Price
- $26.73
- Value
- $922,315
- Dandekar AtulSale
29 Jul 2026, CSBO
- Shares
- 7,500
- Price
- $27.34
- Value
- $205,031
- Bernstein HaroldSale
1 Jul 2026, President, R&D & CMO
- Shares
- 14,609
- Price
- $29.90
- Value
- $436,864
- Coloma Jason VSale
1 Jul 2026, Chief Executive Officer
- Shares
- 34,501
- Price
- $29.98
- Value
- $1.03M
- Dandekar AtulSale
29 Jun 2026, CSBO
- Shares
- 7,500
- Price
- $28.02
- Value
- $210,150
- Coloma Jason VSale
23 Jun 2026, Chief Executive Officer
- Shares
- 23,865
- Price
- $26.05
- Value
- $621,674
- Coloma Jason VSale
22 Jun 2026, Chief Executive Officer
- Shares
- 3,993
- Price
- $26.00
- Value
- $103,821
- Coloma Jason VSale
1 Jun 2026, Chief Executive Officer
- Shares
- 6,643
- Price
- $26.20
- Value
- $174,048
- Bernstein HaroldSale
1 Jun 2026, President, R&D & CMO
- Shares
- 14,853
- Price
- $25.66
- Value
- $381,112
- Dandekar AtulSale
29 May 2026, CSBO
- Shares
- 7,500
- Price
- $26.34
- Value
- $197,554
- Coloma Jason VSale
26 May 2026, Chief Executive Officer
- Shares
- 25,582
- Price
- $26.02
- Value
- $665,516
- Coloma Jason VSale
22 May 2026, Chief Executive Officer
- Shares
- 6,982
- Price
- $26.00
- Value
- $181,532
- Coloma Jason VSale
15 May 2026, Chief Executive Officer
- Shares
- 1,938
- Price
- $26.00
- Value
- $50,388
- Bernstein HaroldSale
14 May 2026, President, R&D & CMO
- Shares
- 15,000
- Price
- $26.22
- Value
- $393,354
Partial trades from one filing are shown in one row, with the average price.
Source: Form 4 filings with the US Securities and Exchange Commission. Grants, option exercises, gifts and tax withholdings are hidden. Not a recommendation to buy.
What happened at Maze Therapeutics
The key events of the last six months from our own data. A click takes you to the matching card.
Sector comparison
702 rated companies in Healthcare
- This company
- 45
- Sector median
- 53
Categories against the sector medianMedian of 702 companies
The median is the middle value: half of the companies in the sector lie above it, half below. Categories with too few comparable companies are left out.
Competitors in Biotechnology
The next larger and next smaller companies by market value
- Celldex TherapeuticsCLDX $2.24B34
- Palvella TherapeuticsPVLA $2.24B44
- ImmunomeIMNM $2.21B36
- Alamar BiosciencesALMR $2.21B47
- Maravai LifeSciences HoldingsMRVI $2.18B38
- Trevi TherapeuticsTRVI $2.18B38
- Aurinia PharmaceuticalsAUPH $2.17B69
- BiohavenBHVN $2.13B42
ETFs that hold Maze Therapeutics
Held by 8 ETFs on Xetra. Shown per index: the ETF with the largest weight.
| ETF | Weight | Cost | Fund size |
|---|---|---|---|
| iShares Nasdaq US Biotechnology UCITS ETF2B70 | 0.12% | 0.35% | €1.25B |
| State Street SPDR Russell 2000 U.S. Small Cap UCITS ETF (Acc)ZPRR | 0.05% | 0.30% | €4.28B |
| Xtrackers Russell 2000 UCITS ETF 1CXRS2 | 0.04% | 0.30% | €2.22B |
Show 4 more
| iShares MSCI World Small Cap UCITS ETFIUSN | 0.01% | 0.35% | €8.27B |
| State Street SPDR MSCI USA Small Cap Value Weighted UCITS ETFZPRV | 0.01% | 0.30% | €964.08M |
| UBS MSCI USA Select Factor Mix UCITS ETF USD accUSUE | 0.00% | 0.25% | €178.55M |
| State Street SPDR MSCI All Country World Investable Market UCITS ETF (Acc)SPYI | 0.00% | 0.17% | €8.84B |
Holdings as reported by the funds via FMP, excluding swap ETFs (their holdings are only collateral).
Data status and sources
- Score
- Daily value of 13 Nov 2026, recalculated nightly
- Price
- Closing price of 12 Nov 2026
- Latest annual report
- Fiscal year 2025, period end 31 Dec 2025
- Source
- Financial statements, ratios and prices from Financial Modeling Prep (FMP), based on the company's reports. MEQIRI calculates the score and fair value from them.
Mandatory disclosures for this rating
- ; time horizon around 12 months
- Rated Weak, published since 7 Nov 2026 (in the score history since 27 Mar 2026)
- End-of-day prices, metrics cached for up to 24 hours
- Score and fair value are estimates from a disclosed model. They are not facts and not a price target.
- Produced by SSM Ventures UG (haftungsbeschränkt), responsible person Sven Brostmeyer, Managing Director, automatically according to the disclosed model.
- Not investment advice. Losses up to and including a total loss are possible. Personal circumstances are not considered.