Iovance Biotherapeutics stock
IOVANASDAQIovance Biotherapeutics, Inc., HealthcareISIN US4622601007
43Score 43 out of 100, Weak
Price and trend
60 / 100
Price history
+200% in one yearThe chart shows daily closes over 16 years, adjusted for stock splits and without dividends. Click into the chart to set a price alert at that price.
Above the 200-day line: the price is 25% above it.
Since January 2026 the 50-day line has been above the 200-day line; the trend has turned up.
Sharply down: the price has fallen very quickly lately (RSI 21).
The price is 49% below its 52-week high. Largest decline in 16 years: 99% (June 2011 to April 2013).
Chart figures for advanced users
- SMA 50$11.35
- Average price of the last 50 trading days, shows the short-term trend.
- SMA 200$6.09
- Average price of the last 200 trading days, shows the long-term trend.
- RSI (14)21
- Relative strength over the last 14 days on a scale from 0 to 100. Above 70 the price counts as overheated, below 30 as sharply fallen.
- MACDbelow the signal line
- Compares a fast and a slow price average. Above its signal line momentum is rising, below it momentum is fading.
- Support$2.13
- The lowest closing price of the last twelve months.
- Resistance$14.86
- The highest closing price of the last twelve months.
Snapshot
Computed from the data by fixed rules, no AI
- Iovance Biotherapeutics, Inc. belongs to the Biotechnology industry (United States) and, with a market value of $3.53B, is number 90 of 296 companies in its industry on MEQIRI.
- In fiscal 2025 it reported revenue of $263.5M (up 60.6% year on year) and a loss of $390.98M.
- For fiscal 2026, analysts expect on average revenue of $415.88M (up 57.8%) and adjusted earnings per share of −$0.44.
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- MEQIRI Score 43 out of 100 (Weak): rank 502 of 714 in Healthcare, median 53.
In plain words
The numbers on this page in plain words, written by an AI
Strengths
- More cash than debtCash $376.32M, financial debt $45.21M.Stability 69
Weaknesses
- DilutionShare count up 158% since 2020.Capital allocation 18
- Volatile share priceVolatility 108% a year over the last 12 months.Stability 69
- Loss-makingLoss of $220.54M over the last 12 months.Fundamentals 17
Its standout strength is momentum, while capital allocation and fundamentals hold the score back.
Daily figure as of 12 Nov 2026
How the score is calculatedScore overview
Fundamental quality fluctuates.
Score history
The full history of up to 20 years comes with MEQIRI Pro.
See plansValuation
Valuation signal
not measuredClosing price of 11 Nov 2026, used by the daily score.
A fair value is not meaningful here, so the signal follows the valuation grade.
Valuation metrics
The model puts the fair value at less than a quarter of the share price. That says more about the assumptions than about the company, so a fair value is not meaningful here and the valuation relies on the P/E and the other metrics.
Calculate with your own assumptionsCompany performance
This shows several years of history with an automatic assessment.
Revenue
In the twelve months to 30 Sep 2026, revenue rose 51.3% on the twelve months before. Revenue turned from negative at the start of the period to positive ($263.5M in the latest year).
Margins
- Gross margin
- Operating margin
- Net margin
In fiscal 2025: gross 34%, operating −151%, net −148%. Last 12 months: net −58%.
Debt & balance sheet
latest quarterDebt is low; no interest coverage is reported.
Earnings
- Next earnings
- 23 Feb 2027in 103 days
- Last reported
- 5 Nov 2026EPS reported −$0.05 (expected −$0.08)above expectations
Analyst estimates
Earnings estimates have barely changed since 15 Oct 2026.
- Earnings per share
- −$0.44+0.4%
- Revenue
- $415.88M+0.3%
- Earnings per share
- −$0.17+1.9%
- Revenue
- $595.54M+0.3%
MEQIRI has stored the estimates since 15 Oct 2026. Until 30 days are available, the card shows the change since that day. Mean estimate according to Financial Modeling Prep. No price target and no recommendation.
Company outlook raised
Share price after the results: +46.1%Second-quarter revenue far above guidance, demand expected to keep rising in the third and fourth quarters, cash now expected to last into the second half of 2028; a full-year guidance update is planned for the third quarter.
“We exceeded our second quarter Amtagvi guidance range of $79 million to $81 million, and second quarter Amtagvi revenue increased roughly 51% over the first quarter of 2026 and 68% year-over-year, reflecting a robust increase in patient demand and adoption.”The outlook is not part of the score and not a recommendation to buy or sell.
From the earnings call on 6 Aug 2026 (fiscal Q2 2026), read by AI.
Insiders
Open-market purchases and sales by executives, board members and major holders
No open-market purchases or sales in the last 6 months.
Source: Form 4 filings with the US Securities and Exchange Commission. Grants, option exercises, gifts and tax withholdings are hidden. Not a recommendation to buy.
What happened at Iovance Biotherapeutics
The key events of the last six months from our own data. A click takes you to the matching card.
Sector comparison
714 rated companies in Healthcare
- This company
- 43
- Sector median
- 53
Categories against the sector medianMedian of 714 companies
The median is the middle value: half of the companies in the sector lie above it, half below. Categories with too few comparable companies are left out.
Competitors in Biotechnology
The next larger and next smaller companies by market value
- Amylyx PharmaceuticalsAMLX $4.09B43
- AbCellera BiologicsABCL $3.9B38
- Tarsus PharmaceuticalsTARS $3.78B43
- Enliven TherapeuticsELVN $3.77B45
- Denali TherapeuticsDNLI $3.72B37
- Viking TherapeuticsVKTX $3.63B34
- Legend BiotechLEGN $3.61B37
- Arcutis BiotherapeuticsARQT $3.59B62
ETFs that hold Iovance Biotherapeutics
Held by 12 ETFs on Xetra. Shown per index: the ETF with the largest weight.
| ETF | Weight | Cost | Fund size |
|---|---|---|---|
| iShares Healthcare Innovation UCITS ETF2B78 | 0.28% | 0.40% | €1.49B |
| iShares Ageing Population UCITS ETF2B77 | 0.26% | 0.40% | €807M |
| iShares Nasdaq US Biotechnology UCITS ETF2B70 | 0.23% | 0.35% | €1.21B |
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| State Street SPDR Russell 2000 U.S. Small Cap UCITS ETF (Acc)ZPRR | 0.11% | 0.30% | €4.22B |
| Xtrackers Russell 2000 UCITS ETF 1CXRS2 | 0.11% | 0.30% | €2.17B |
| iShares MSCI USA Small Cap CTB Enhanced ESG UCITS ETFSXRG | 0.04% | 0.43% | €2.48B |
| State Street SPDR MSCI World Small Cap UCITS ETF (Acc)ZPRS | 0.03% | 0.45% | €1.53B |
| iShares MSCI World Small Cap CTB Enhanced ESG UCITS ETFCBUG | 0.02% | 0.35% | €434.1M |
Holdings as reported by the funds via FMP, excluding swap ETFs (their holdings are only collateral).
Data status and sources
- Score
- Daily value of 12 Nov 2026, recalculated nightly
- Price
- Closing price of 12 Nov 2026
- Latest annual report
- Fiscal year 2025, period end 31 Dec 2025
- Source
- Financial statements, ratios and prices from Financial Modeling Prep (FMP), based on the company's reports. MEQIRI calculates the score and fair value from them.
Mandatory disclosures for this rating
- ; time horizon around 12 months
- Rated Weak, published since 7 Nov 2026 (in the score history since 31 Oct 2011)
- End-of-day prices, metrics cached for up to 24 hours
- Score and fair value are estimates from a disclosed model. They are not facts and not a price target.
- Produced by SSM Ventures UG (haftungsbeschränkt), responsible person Sven Brostmeyer, Managing Director, automatically according to the disclosed model.
- Not investment advice. Losses up to and including a total loss are possible. Personal circumstances are not considered.