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Ionis Pharmaceuticals stock: balance sheet and debt

IONS
$27.31Closing price of 12 Nov 2026MEQIRI Score 32 out of 100

Ionis Pharmaceuticals has a debt to equity ratio of 5.35.

Daily figure as of 13 Nov 2026

Debt / Equity
5.35
Interest coverage
−3.4x
Current ratio
3.83
Cash & equivalents
$2.68B
Total assets
$3.52B
Equity ratio
13.9%
Goodwill
not reported separately
Net debt
−$62.68M
More cash than debt

Total assets and equity ratio

How large the balance sheet of Ionis Pharmaceuticals, Inc. is, how much of it is equity and how much is goodwill from acquisitions.

Equity ratio

Figures as a table
YearTotal assetsGoodwill and intangible assetsof which goodwillEquity ratioNet debt
2006$255.91M$38.27Mnot split out38.3%−$53M
2007$258.86M$36.86Mnot split out4.0%−$23.62M
2008$574.15M$33.12Mnot split out18.2%−$316.5M
2009$657.18M$30.45Mnot split out46.0%−$433.46M
2010$550.48M$15.82Mnot split out44.4%−$317.95M
2011$484.89M$16.26Mnot split out35.4%−$128.95M
2012$545.69M$25.23Mnot split out33.5%−$188.65M
2013$847.16M$20.09Mnot split out44.7%−$482.83M
2014$955.81M$19.88Mnot split out27.0%−$360.6M
2015$947.9M$19.32Mnot split out21.2%−$333.36M
2016$912.47M$20.37Mnot split out10.9%−$91.17M
2017$1.32B$22Mnot split out27.6%−$428.21M
2018$2.67B$24.03Mnot split out44.5%−$1.44B
2019$3.23B$25.67Mnot split out52.1%−$1.73B
2020$2.39B$27.94Mnot split out31.1%−$983.45M
2021$2.61B$29.01Mnot split out29.5%−$882.13M
2022$2.53Bnot reported separatelynot reported separately22.6%−$628.21M
2023$2.99Bnot reported separatelynot reported separately12.9%−$877.66M
2024$3Bnot reported separatelynot reported separately19.6%−$881.09M
2025$3.52Bnot reported separatelynot reported separately13.9%−$62.68M

The equity ratio divides total equity, including non-controlling interests, by total assets. Net debt is debt minus cash and short-term investments; a negative figure means cash exceeds debt. In years without separate goodwill, the table shows the sum of goodwill and intangible assets, because the data do not list goodwill separately there.

Equity and debt

What the company owns and owes

  • Cash & equivalents
  • Equity
  • Debt
Figures as a table
YearCash & equivalentsEquityDebtDebt / Equity
2006$193.33M$68.56M$140.34M1.43
2007$193.72M$872K$170.1M16.61
2008$491M$67.09M$174.5M1.67
2009$574.31M$291.72M$140.85M0.47
2010$472.35M$244.54M$154.41M0.63
2011$343.66M$171.43M$214.72M1.25
2012$408.07M$182.77M$219.42M1.2
2013$708.86M$378.39M$226.03M0.6
2014$810.71M$257.78M$450.11M1.75
2015$803.98M$200.79M$470.62M2.34
2016$665.22M$99.57M$574.06M5.77
2017$1.02B$281.01M$594.5M1.63
2018$2.08B$1.05B$641.81M0.54
2019$2.5B$1.47B$771.98M0.46
2020$1.89B$743.28M$908.93M1.22
2021$2.13B$771.74M$1.25B1.62
2022$2B$572.89M$1.37B2.39
2023$2.33B$386.69M$1.45B3.76
2024$2.3B$588.35M$1.42B2.41
2025$2.68B$489.09M$2.61B5.35

Debt to equity divides debt by total equity, including non-controlling interests, as S&P calculates it. The equity column shows the part that belongs to shareholders.

Data status and sources

Score
Daily value of 13 Nov 2026, recalculated nightly
Price
Closing price of 12 Nov 2026
Latest annual report
Fiscal year 2025, period end 31 Dec 2025
Source
Financial statements, ratios and prices from Financial Modeling Prep (FMP), based on the company's reports. MEQIRI calculates the score and fair value from them.

Mandatory disclosures for this rating

  • ; time horizon around 12 months
  • Rated Weak, published since 7 Nov 2026 (in the score history since 28 Feb 2021)
  • Valuation signal Fairly valued since 7 Nov 2026
  • End-of-day prices, metrics cached for up to 24 hours
  • Score and fair value are estimates from a disclosed model. They are not facts and not a price target.
  • Produced by SSM Ventures UG (haftungsbeschränkt), responsible person Sven Brostmeyer, Managing Director, automatically according to the disclosed model.
  • Not investment advice. Losses up to and including a total loss are possible. Personal circumstances are not considered.

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