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CRISPR Therapeutics stock

CRSPNASDAQ

CRISPR Therapeutics AG, HealthcareISIN CH0334081137

$42.62▼ $3.13 (−6.8%)Closing price of 12 Nov 2026

37Score 37 out of 100, Weak

Turn on early warning

Price and trend

48 / 100

Price history

−18% in one year

The chart shows daily closes over 10 years, adjusted for stock splits and without dividends. Click into the chart to set a price alert at that price.

Long-term trend

Below the 200-day line: the price is 19% below it.

Trend change

Since November 2026 the 50-day line has been below the 200-day line; the trend has turned down.

Momentum

Normal: the price is neither overheated nor sold off (RSI 36).

Distance to the high

The price is 31% below its 52-week high. Largest decline in 10 years: 85% (January 2021 to April 2025).

Chart figures for advanced users
SMA 50$52.38
Average price of the last 50 trading days, shows the short-term trend.
SMA 200$52.58
Average price of the last 200 trading days, shows the long-term trend.
RSI (14)36
Relative strength over the last 14 days on a scale from 0 to 100. Above 70 the price counts as overheated, below 30 as sharply fallen.
MACDbelow the signal line
Compares a fast and a slow price average. Above its signal line momentum is rising, below it momentum is fading.
Support$42.62
The lowest closing price of the last twelve months.
Resistance$61.89
The highest closing price of the last twelve months.
Market cap
$4.44B
Div. yield
no dividend
Loss
Loss expected
Fair value
no data

Snapshot

Computed from the data by fixed rules, no AI

  • CRISPR Therapeutics AG belongs to the Biotechnology industry (Switzerland) and, with a market value of $4.13B, is number 81 of 296 companies in its industry on MEQIRI.
  • In fiscal 2025 it reported revenue of $3.51M (down 90% year on year) and a loss of $581.6M.
  • MEQIRI Score 37 out of 100 (Weak): rank 595 of 714 in Healthcare, median 53.

In plain words

The numbers on this page in plain words, written by an AI

Strengths

  • Growing faster than its industryRevenue up 37.3% a year since 2020, Biotechnology median 19.7%.Growth 70
  • More cash than debtCash $2.27B, financial debt $779.83M.Stability 67

Weaknesses

  • DilutionShare count up 36% since 2020.Capital allocation 18
  • Loss-makingLoss of $456.14M over the last 12 months.Fundamentals 17
  • Negative free cash flowFree cash flow −$379.19M over the last 12 months.Fundamentals 17
37/ 100
MEQIRI Score
Weak

Its standout strength is growth, while fundamentals and profitability hold the score back.

Daily figure as of 12 Nov 2026

How the score is calculated

Score overview

Score since yesterday from 36 to 37.

Fundamental quality fluctuates.

Profit consistency20% of years
Cash conversion (free cash flow to earnings, 12 months)not measured
ROIC (12 months)−16.7%
Positive free cash flow20% of years
How this category is measured

Score history

The full history of up to 20 years comes with MEQIRI Pro.

See plans

Valuation

Valuation signal

not measured
Price
$45.75
Fair value
not computable
Gap to fair value
no data

Closing price of 11 Nov 2026, used by the daily score.

No fair value can be calculated for this stock, so the signal follows the valuation grade.

Valuation metrics

no data
no data
Fair value (model)
no data

No fair value can be calculated for this stock from the available figures.

Calculate with your own assumptions

Company performance

This shows several years of history with an automatic assessment.

Revenue

12 years

In fiscal 2025, revenue fell 90% on the prior year. Up to 2022 the bars include businesses that were later spun off or sold. On a comparable basis, as restated in the SEC annual reports, revenue grew 37.3% a year.

Margins

12 years
  • Gross margin
  • Operating margin
  • Net margin

In fiscal 2025: gross −6537%, operating −16191%, net −16570%. Last 12 months: net −100%.

Debt & balance sheet

latest quarter
0.47
no data
16.21
Cash & equivalents
$2.27B

Debt is moderate; no interest coverage is reported.

Earnings

Next earnings
11 Feb 2027in 91 days
Last reported
2 Nov 2026EPS reported −$1.15 (expected −$1.04)below expectations

Analyst estimates

Analysts have cut their 2027 earnings estimate by 4.3% since 15 Oct 2026. Falling estimates often precede bad news.

Fiscal 202613 analysts
Earnings per share
−$4.50−1.8%
Revenue
$34.15M−12.9%
Fiscal 202715 analysts
Earnings per share
−$3.55−4.3%
Revenue
$119.98M−10.6%

MEQIRI has stored the estimates since 15 Oct 2026. Until 30 days are available, the card shows the change since that day. Mean estimate according to Financial Modeling Prep. No price target and no recommendation.

Insiders

Open-market purchases and sales by executives, board members and major holders

All insider purchases

No open-market purchases in the last 6 months. 5 insiders sold, $5.09M in total.

Sales say less than purchases: many insiders sell on a fixed plan, for taxes or to diversify.

  • Kulkarni SamarthSale

    19 Oct 2026, Chief Executive Officer

    Shares
    47,837
    Price
    $49.78
    Value
    $2.38M
  • George SimeonSale

    14 Oct 2026, Board

    Shares
    14,514
    Price
    $49.63
    Value
    $720,373
  • Kasinger James R.Sale

    14 Oct 2026, General Counsel and Secretary

    Shares
    1,040
    Price
    $49.26
    Value
    $51,230
Show 5 more
  • Kulkarni SamarthSale

    14 Oct 2026, Chief Executive Officer

    Shares
    4,098
    Price
    $49.26
    Value
    $201,867
  • Kasinger James R.Sale

    6 Oct 2026, General Counsel and Secretary

    Shares
    1,990
    Price
    $60.04
    Value
    $119,481
  • Kasinger James R.Sale

    22 Sept 2026, General Counsel and Secretary

    Shares
    10,400
    Price
    $60.24
    Value
    $626,460
  • Behbahani AliSale

    17 Sept 2026, Board

    Shares
    13,679
    Price
    $57.09
    Value
    $780,935
  • Patel NaimishSale

    29 May 2026, Chief Medical Officer

    Shares
    3,786
    Price
    $55.62
    Value
    $210,577

Source: Form 4 filings with the US Securities and Exchange Commission. Grants, option exercises, gifts and tax withholdings are hidden. Not a recommendation to buy.

What happened at CRISPR Therapeutics

The key events of the last six months from our own data. A click takes you to the matching card.

Sector comparison

714 rated companies in Healthcare

Rank 595 of 714
595/ 714
This company
37
Sector median
53

Categories against the sector medianMedian of 714 companies

Profitability12 (median 37)25 below the median
Growth70 (median 53)17 above the median
Fundamentals17 (median 46)29 below the median
Stability67 (median 67)0 at the median
Capital allocation18 (median 39)21 below the median
Technical analysis48 (median 70)22 below the median
Momentum30 (median 71)41 below the median

The median is the middle value: half of the companies in the sector lie above it, half below. Categories with too few comparable companies are left out.

Competitors in Biotechnology

The next larger and next smaller companies by market value

All 296 Biotechnology stocks

ETFs that hold CRISPR Therapeutics

Held by 16 ETFs on Xetra. Shown per index: the ETF with the largest weight.

ETFWeightCostFund size
Global X Genomics & Biotechnology UCITS ETFGN0M2.50%0.50%€127.06M
L&G Healthcare Technology & Innovation UCITS ETFXMLH1.54%0.49%€318.39M
iShares Ageing Population UCITS ETF2B770.42%0.40%€807M
Show 5 more

Holdings as reported by the funds via FMP, excluding swap ETFs (their holdings are only collateral).

Data status and sources

Score
Daily value of 12 Nov 2026, recalculated nightly
Price
Closing price of 12 Nov 2026
Latest annual report
Fiscal year 2025, period end 31 Dec 2025
Source
Financial statements, ratios and prices from Financial Modeling Prep (FMP), based on the company's reports. MEQIRI calculates the score and fair value from them.

Mandatory disclosures for this rating

  • ; time horizon around 12 months
  • Rated Weak, published since 7 Nov 2026 (in the score history since 31 Aug 2022)
  • End-of-day prices, metrics cached for up to 24 hours
  • Score and fair value are estimates from a disclosed model. They are not facts and not a price target.
  • Produced by SSM Ventures UG (haftungsbeschränkt), responsible person Sven Brostmeyer, Managing Director, automatically according to the disclosed model.
  • Not investment advice. Losses up to and including a total loss are possible. Personal circumstances are not considered.

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